Research Article | | Peer-Reviewed

Evaluation of the Glycemic Index of Protein- and Fiber-Rich Biscuits Designed for Healthy Snacking

Received: 22 October 2024     Accepted: 18 November 2024     Published: 9 December 2024
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Abstract

The glycemic index (GI) is a measure that classifies carbohydrate-rich foods according to their impact on blood glucose levels. Foods with a low GI are digested and absorbed at a slower rate, leading to a gradual increase in blood sugar, which helps maintain steady energy levels and reduce the risk of chronic conditions like diabetes and cardiovascular disease. This study evaluated the GI of protein- and fiber-rich biscuits to determine their suitability as a low-GI food option. Using a randomized crossover design, participants aged 18–45 years with a body mass index of 18.5–22.9 kg/m² were instructed to consume both test and reference foods on separate occasions. Blood samples were collected at multiple time points post-consumption, and the GI was determined by calculating the incremental area under the curve (IAUC) for the test food and expressing it as a percentage of the reference food’s IAUC. The GI of the nutritionally formulated diabetic biscuits (test food) was estimated to be 54±2, classifying them as low-GI food. These biscuits led to a significant reduction in capillary blood glucose levels at several post-consumption intervals, supporting their potential as a dietary option for prediabetic and diabetic individuals. Our findings indicate that high-protein, high-fiber, low-GI biscuits may offer nutritional benefits for prediabetic and diabetic individuals by supporting blood glucose control. This study highlights the potential role of low-GI foods in diabetes management, emphasizes the importance of GI testing for foods aimed at glycemic control, and reinforces the need for transparent nutritional labeling to impact consumer choices.

Published in Journal of Food and Nutrition Sciences (Volume 12, Issue 6)
DOI 10.11648/j.jfns.20241206.15
Page(s) 287-293
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Glycemic Index, Low-GI Food, Blood Glucose, High-fiber Snacks, Diabetes Management, Protein-rich Snacks, Obesity, IAUC

References
[1] Sacks, F. M., Carey, V. J., Anderson, C. A. M., Miller, E. R., III, Copeland, T., Charleston, J., et al. Effects of High vs Low Glycemic Index of Dietary Carbohydrate on Cardiovascular Disease Risk Factors and Insulin Sensitivity: The OmniCarb Randomized Clinical Trial. JAMA. 2014, 312(23), 2531–2541.
[2] Ma, Y., Olendzki, B. C., Merriam, P. A., Chiriboga, D. E., Culver, A. L., Li, W., et al. A Randomized Clinical Trial Comparing Low-Glycemic Index versus ADA Dietary Education among Individuals with Type 2 Diabetes. Nutrition (Burbank, Los Angeles County, Calif.). 2008, 24(1), 45–56.
[3] Vlachos, D., Malisova, S., Lindberg, F. A., Karaniki, G. Glycemic Index (GI) or Glycemic Load (GL) and Dietary Interventions for Optimizing Postprandial Hyperglycemia in Patients with T2 Diabetes: A Review. Nutrients. 2020, 12(6), 1561.
[4] Esfahani, A., Wong, J. M. W., Mirrahimi, A., Srichaikul, K., Jenkins, D. J. A., Kendall, C. W. C. The Glycemic Index: Physiological Significance. Journal of the American College of Nutrition. 2009, 28(sup4), 439S-445S.
[5] Fujiwara, Y., Eguchi, S., Murayama, H., Takahashi, Y., Toda, M., Imai, K., et al. Relationship between diet/exercise and pharmacotherapy to enhance the GLP‐1 levels in type 2 diabetes. Endocrinology, Diabetes & Metabolism. 2019, 2(3), e00068.
[6] Zafar, M. I., Mills, K. E., Zheng, J., Regmi, A., Hu, S. Q., Gou, L., et al. Low-glycemic index diets as an intervention for diabetes: a systematic review and meta-analysis. The American Journal of Clinical Nutrition. 2019, 110(4), 891–902.
[7] Arvidsson-Lenner, R., Asp, N. G., Bryngelsson, S., Haapa, E., Jarvi, A., Karlström, B., et al. Glycaemic Index. Relevance for health, dietary recommendations and food labelling. Food & Nutrition Research. 2004, 48(2), 84-94.
[8] Murillo, S., Mallol, A., Adot, A., Juárez, F., Coll, A., Gastaldo, I., et al. Culinary strategies to manage glycemic response in people with type 2 diabetes: A narrative review. Frontiers in Nutrition. 2022, 9, 1025993.
[9] Kim, H. K., Nanba, T., Ozaki, M., Chijiki, H., Takahashi, M., Fukazawa, M., et al. Effect of the Intake of a Snack Containing Dietary Fiber on Postprandial Glucose Levels. Foods. 2020, 9(10), 1500.
[10] Dodd, H., Williams, S., Brown, R., Venn, B. Calculating meal glycemic index by using measured and published food values compared with directly measured meal glycemic index123. The American Journal of Clinical Nutrition. 2011, 94(4), 992–996.
[11] Chlup, R., Sečkař, P., Zapletalová, J., Langová, K., Kudlová, P., Chlupová, K., et al. Automated Computation of Glycemic Index for Foodstuffs Using Continuous Glucose Monitoring. Journal of Diabetes Science and Technology (Online). 2008, 2(1), 67–75.
[12] Augustin, L. S. A., Kendall, C. W. C., Jenkins, D. J. A., Willett, W. C., Astrup, A., Barclay, A. W., et al. Glycemic index, glycemic load and glycemic response: An International Scientific Consensus Summit from the International Carbohydrate Quality Consortium (ICQC). Nutrition, Metabolism and Cardiovascular Diseases. 2015, 25(9), 795–815.
[13] Wolever, T. M. S., Meynier, A., Jenkins, A. L., Brand-Miller, J. C., Atkinson, F. S., Gendre, D., et al. Glycemic Index and Insulinemic Index of Foods: An Interlaboratory Study Using the ISO 2010 Method. Nutrients. 2019, 11(9), 2218.
[14] Atkinson, F. S., Foster-Powell, K., Brand-Miller, J. C. International Tables of Glycemic Index and Glycemic Load Values: 2008. Diabetes Care. 2008, 31(12), 2281–2283.
[15] Li, D., Zhang, P., Guo, H., Ling, W. Taking a low glycemic index multi-nutrient supplement as breakfast improves glycemic control in patients with type 2 diabetes mellitus: a randomized controlled trial. Nutrients. 2014, 6(12), 5740–5755.
[16] Stewart, M. L., Zimmer, J. P. A High Fiber Cookie Made with Resistant Starch Type 4 Reduces Post-Prandial Glucose and Insulin Responses in Healthy Adults. Nutrients. 2017, 9(3), 237.
[17] Bhoite, R., Shobana, S., Pratti, V. L., Satyavrat, V., Gayathri, R., Anjana, R. M., et al. Estimation of glycemic index in a dietary formulation targeted to support enteral and oral nutritional needs. Discover Food. 2023, 3(1), 5.
[18] Yang, J., Park, H. J., Hwang, W., Kim, T. H., Kim, H., Oh, J., et al. Changes in the glucose and insulin responses according to high-protein snacks for diabetic patients. Nutrition Research and Practice. 2021, 15(1), 54–65.
[19] Magliano, D. J., Boyko, E. J., IDF Diabetes Atlas 10th edition scientific committee. Global picture. In IDF Diabetes Atlas [Internet], 10th Ed. Brussels: International Diabetes Federation; 2021.
[20] Nuttall, F. Q., Gannon, M. C. Metabolic response of people with type 2 diabetes to a high protein diet. Nutrition & Metabolism. 2004, 1(1), 6.
[21] Nogueira, A. de C., Steel, C. J. Protein enrichment of biscuits: a review. Food Reviews International. 2018, 34(8), 796–809.
[22] Malaeb, S., Bakker, C., Chow, L. S., Bantle, A. E. High-Protein Diets for Treatment of Type 2 Diabetes Mellitus: A Systematic Review. Advances in Nutrition. 2019, 10(4), 621–633.
[23] Barber, T. M., Kabisch, S., Pfeiffer, A. F. H., Weickert, M. O. The Health Benefits of Dietary Fibre. Nutrients. 2020, 12(10), 3209.
[24] Campbell, M. D., Walker, M., Trenell, M. I., Stevenson, E. J., Turner, D., Bracken, R. M., et al. A Low–Glycemic Index Meal and Bedtime Snack Prevents Postprandial Hyperglycemia and Associated Rises in Inflammatory Markers, Providing Protection From Early but Not Late Nocturnal Hypoglycemia Following Evening Exercise in Type 1 Diabetes. Diabetes Care. 2014, 37(7), 1845–1853.
[25] Rizkalla, S. W., Bellisle, F., Slama, G. Health benefits of low glycaemic index foods, such as pulses, in diabetic patients and healthy individuals. British Journal of Nutrition. 2002, 88(S3), 255–262.
[26] Miller, J. Importance of glycemic index in diabetes. The American Journal of Clinical Nutrition. 1994, 59(3), 747S-752S.
[27] Gitanjali, Singh, V. Development and nutritional evaluation of low glycemic index recipe from ragi and pulses for diabetes. International Journal of Chemical Studies. 2020, 8(2), 2737–2741.
[28] Bakare, A. H., Adeola, A. A., Otesile, I., Obadina, A. O., Afolabi, W. A., Adegunwa, M. O., et al. Nutritional, Texture, and Sensory Properties of composite biscuits produced from breadfruit and wheat flours enriched with edible fish meal. Food Science & Nutrition. 2020, 8(11), 6226–6246.
Cite This Article
  • APA Style

    Bhoite, R., Immadisetti, P., Kalpana, N., Padmavathi, S., Gayathri, R., et al. (2024). Evaluation of the Glycemic Index of Protein- and Fiber-Rich Biscuits Designed for Healthy Snacking. Journal of Food and Nutrition Sciences, 12(6), 287-293. https://doi.org/10.11648/j.jfns.20241206.15

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    ACS Style

    Bhoite, R.; Immadisetti, P.; Kalpana, N.; Padmavathi, S.; Gayathri, R., et al. Evaluation of the Glycemic Index of Protein- and Fiber-Rich Biscuits Designed for Healthy Snacking. J. Food Nutr. Sci. 2024, 12(6), 287-293. doi: 10.11648/j.jfns.20241206.15

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    AMA Style

    Bhoite R, Immadisetti P, Kalpana N, Padmavathi S, Gayathri R, et al. Evaluation of the Glycemic Index of Protein- and Fiber-Rich Biscuits Designed for Healthy Snacking. J Food Nutr Sci. 2024;12(6):287-293. doi: 10.11648/j.jfns.20241206.15

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  • @article{10.11648/j.jfns.20241206.15,
      author = {Rachana Bhoite and Praneeth Immadisetti and Natarajan Kalpana and Soundararajan Padmavathi and Rajagopal Gayathri and Vasudevan Sudha and Ranjit Mohan Anjana and Viswanathan Mohan},
      title = {Evaluation of the Glycemic Index of Protein- and Fiber-Rich Biscuits Designed for Healthy Snacking
    },
      journal = {Journal of Food and Nutrition Sciences},
      volume = {12},
      number = {6},
      pages = {287-293},
      doi = {10.11648/j.jfns.20241206.15},
      url = {https://doi.org/10.11648/j.jfns.20241206.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfns.20241206.15},
      abstract = {The glycemic index (GI) is a measure that classifies carbohydrate-rich foods according to their impact on blood glucose levels. Foods with a low GI are digested and absorbed at a slower rate, leading to a gradual increase in blood sugar, which helps maintain steady energy levels and reduce the risk of chronic conditions like diabetes and cardiovascular disease. This study evaluated the GI of protein- and fiber-rich biscuits to determine their suitability as a low-GI food option. Using a randomized crossover design, participants aged 18–45 years with a body mass index of 18.5–22.9 kg/m² were instructed to consume both test and reference foods on separate occasions. Blood samples were collected at multiple time points post-consumption, and the GI was determined by calculating the incremental area under the curve (IAUC) for the test food and expressing it as a percentage of the reference food’s IAUC. The GI of the nutritionally formulated diabetic biscuits (test food) was estimated to be 54±2, classifying them as low-GI food. These biscuits led to a significant reduction in capillary blood glucose levels at several post-consumption intervals, supporting their potential as a dietary option for prediabetic and diabetic individuals. Our findings indicate that high-protein, high-fiber, low-GI biscuits may offer nutritional benefits for prediabetic and diabetic individuals by supporting blood glucose control. This study highlights the potential role of low-GI foods in diabetes management, emphasizes the importance of GI testing for foods aimed at glycemic control, and reinforces the need for transparent nutritional labeling to impact consumer choices.
    },
     year = {2024}
    }
    

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  • TY  - JOUR
    T1  - Evaluation of the Glycemic Index of Protein- and Fiber-Rich Biscuits Designed for Healthy Snacking
    
    AU  - Rachana Bhoite
    AU  - Praneeth Immadisetti
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    AU  - Soundararajan Padmavathi
    AU  - Rajagopal Gayathri
    AU  - Vasudevan Sudha
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    AU  - Viswanathan Mohan
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    JF  - Journal of Food and Nutrition Sciences
    JO  - Journal of Food and Nutrition Sciences
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    EP  - 293
    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.jfns.20241206.15
    AB  - The glycemic index (GI) is a measure that classifies carbohydrate-rich foods according to their impact on blood glucose levels. Foods with a low GI are digested and absorbed at a slower rate, leading to a gradual increase in blood sugar, which helps maintain steady energy levels and reduce the risk of chronic conditions like diabetes and cardiovascular disease. This study evaluated the GI of protein- and fiber-rich biscuits to determine their suitability as a low-GI food option. Using a randomized crossover design, participants aged 18–45 years with a body mass index of 18.5–22.9 kg/m² were instructed to consume both test and reference foods on separate occasions. Blood samples were collected at multiple time points post-consumption, and the GI was determined by calculating the incremental area under the curve (IAUC) for the test food and expressing it as a percentage of the reference food’s IAUC. The GI of the nutritionally formulated diabetic biscuits (test food) was estimated to be 54±2, classifying them as low-GI food. These biscuits led to a significant reduction in capillary blood glucose levels at several post-consumption intervals, supporting their potential as a dietary option for prediabetic and diabetic individuals. Our findings indicate that high-protein, high-fiber, low-GI biscuits may offer nutritional benefits for prediabetic and diabetic individuals by supporting blood glucose control. This study highlights the potential role of low-GI foods in diabetes management, emphasizes the importance of GI testing for foods aimed at glycemic control, and reinforces the need for transparent nutritional labeling to impact consumer choices.
    
    VL  - 12
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