Volume 3, Issue 3-1, May 2015, Page: 1-4
Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats
Mari Kimoto, Physiological Laboratories, Japan Women's University, Tokyo, Japan
Jorge L. Zeredo, Graduate Program in Health Sciences and Technology, University of Brasilia, Brasilia, Brazil; Integrative Sensory Physiology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
Masato S. Ota, Laboratory of Biochemistry and Food Biology, Japan Women's University, Tokyo, Japan
Zenro Nihei, Integrative Sensory Physiology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
Kazuo Toda, Physiological Laboratories, Japan Women's University, Tokyo, Japan; Integrative Sensory Physiology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
Received: Dec. 15, 2014;       Accepted: Dec. 16, 2014;       Published: Feb. 27, 2015
DOI: 10.11648/j.jfns.s.2015030301.11      View  3617      Downloads  185
We investigated the effects of somatostatin on the ileal movements after gravity stress and compared these effects between male and female rats. Using an in vitro preparation, measurements of ileal movements evoked by somatostatin application were done at 1, 3, 15 and 30 days after 3G gravity loading-conditioning. Mixed phasic and tonic patterns were observed in the ileal muscle activities. Gravity-stress decreased or antagonized somatostatin inhibitory effects on tonic ileal contraction at an early stage (at day 3) in females, but not in males, indicating that sex differences exist in the way that changes of somatostatin sensitivity is modulated by stress conditioning.
Somatostatin, Gravity Stress, Ileum, Sex Difference, Rat
To cite this article
Mari Kimoto, Jorge L. Zeredo, Masato S. Ota, Zenro Nihei, Kazuo Toda, Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats, Journal of Food and Nutrition Sciences. Special Issue: Effects of Foods on Gastrointestinal, Metabolic and Immunological Function. Vol. 3, No. 3-1, 2015, pp. 1-4. doi: 10.11648/j.jfns.s.2015030301.11
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