Volume 7, Issue 3, May 2019, Page: 49-55
Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women
Kaori Kuzawa, Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan
Akihiro Yoshida, Department of Clinical Laboratory, Sakashita Hospital, Nakatsugawa, Japan
Ikuko Tsukamoto, Faculty of Medicine, Kagawa University, Miki, Japan
Masaaki Tokuda, Faculty of Medicine, Kagawa University, Miki, Japan
Michitaka Naito, Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan
Received: Aug. 2, 2019;       Accepted: Aug. 24, 2019;       Published: Sep. 19, 2019
DOI: 10.11648/j.jfns.20190703.12      View  32      Downloads  9
Abstract
Aim: Our previous study demonstrated that the ingestion of fructose with fat exacerbated and delayed postprandial lipid metabolism (J Atheroscler Thromb 2013; 20: 591). Herein, we investigated the effect of ingesting a water-soluble dietary fiber, resistant maltodextrin (RMD), which has been reported to be effective for ameliorating postprandial glycemia and lipidemia, on fructose-induced postprandial hyperlipidemia in healthy young women. Methods: Healthy young Japanese women with apolipoprotein E3/3 phenotype were enrolled. They underwent 4 test trials in a randomized crossover design: fat cream (0.35 g/kg of fat; F trial), fat cream with RMD (5 g; FR trial), fat cream with fructose (0.5 g/kg; FFr trial), and fat cream with fructose and RMD (FFrR trial). Blood samples were taken before (0) and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: The serum glucose and insulin concentrations peaked at 0.5 h in the FFr and FFrR trials, and no difference was observed between these trials. There was no increase in glucose concentration in the F or FR trials. The serum triglyceride and apolipoprotein B48 concentrations peaked at 4 h in all trials. In the F and FR trials (but not in the FFr and FFrR trials), the serum triglyceride concentration returned to the fasting level at 6 h. In all trials, the apolipoprotein B48 concentration did not return to baseline at 6 h. Conclusion: Co-ingestion of RMD did not significantly inhibit fructose-induced postprandial hyperlipidemia.
Keywords
Resistant Maltodextrin, Fructose, Postprandial Hyperlipidemia, Triglyceride-Rich Lipoprotein, Remnant
To cite this article
Kaori Kuzawa, Akihiro Yoshida, Ikuko Tsukamoto, Masaaki Tokuda, Michitaka Naito, Effect of Ingesting Resistant Maltodextrin on Postprandial Hyperlipidemia Induced by Fructose in Young Women, Journal of Food and Nutrition Sciences. Vol. 7, No. 3, 2019, pp. 49-55. doi: 10.11648/j.jfns.20190703.12
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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